The COVID-19 pandemic has set off a wave of research activities across the world, aimed at finding clues that would allow us to design effective therapeutics and vaccines. In one such effort, a team of researchers from the Indian Institute of Technology, Kanpur, have initiated a study into the molecular dynamics of the process via which the novel coronavirus attaches to cells of the human respiratory system.
In one of India's first student-led scientific conferences, Hy-Sci (Hyderabad Science) 2019 brought together graduate students, researchers, and science professionals on a single platform to discuss science as well as to deliberate on the scientific ecosystem in India.
Tuberculosis is an infectious disease that kills lakhs of Indians every year. Early detection of the disease is key to administering treatment; however, this has been hampered by the fact that current diagnostic techniques are often costly and time-consuming. Now, researchers from the Indian Institute of Science, Bengaluru, have come up with an inexpensive paper-based diagnostic device for tuberculosis detection.
As the problem of antibiotic resistance mounts worldwide, there is a pressing need for identifying and testing novel drug targets. Recently, a team of researchers from the Indian Institute of Science Education and Research (IISER), Pune, and the Central Drug Research Institute (CSIR-CDRI), Lucknow, has identified a protein pathway in an antibiotic-resistant bacterial strain which can be targeted using a small molecule to effectively kill the bacteria.
A new study by researchers at the Indian Institute of Technology, Kanpur has identified a small molecule drug which shows therapeutic promise against Huntington's disease, a fatal neurodegenerative disorder. The molecule prevents the formation of protein clumps or aggregates which are detrimental for the health of neurons.
A recurring challenge for combination cancer therapy has been delivering drugs with widely differing properties to the tumour site. Now, researchers at the Regional Centre for Biotechnology, Faridabad, and Amity University, Haryana, have come up with a novel strategy for combining three different drugs into a single package that can induce tumour shrinkage when injected.
The Hemidactylus geckos have evolved into several distinct species in the Indian peninsula, some of which often show up as uninvited guests in our houses. Researchers at the Center for Ecological Sciences, Indian Institute of Science (CES-IISc) have shown that differences in morphology among species of ground-dwelling geckos can indicate changes in the past climate of peninsular India.