News Older →

• 

  Novel role of FOXO, a transcription factor, in egg cell development

  Banya Kar

  A recent study by researchers at the National Institute of Immunology (NII), New Delhi, led by Arnab Mukhopadhyay, used C. elegans to show how damage to somatic tissues in the body can influence the development of reproductive cells—particularly eggs. They found that DNA damage signals from uterine tissue can stop egg cell formation through a key FOXO transcription factor, which is a highly conserved protein across different organisms.

  ---

• 

  Using peptides and lipids to deliver RNA interference safely into cells

  Rohini Subrahmanyam

  A team of researchers from Indian Institute of Science Education and Research (IISER) Kolkata and IISER Pune engineered a lipopeptide-based siRNA transporter, ensuring that siRNAs could efficiently enter the cytoplasm of the cells in functional form and perform gene silencing.

  ---

• 

  Study reveals promising biomarker for predicting patient response to cancer immunotherapy

  Purva Variyar

  In a recent study, a team of researchers from National Centre for Biological Sciences (TIFR), Bengaluru, and Centre for BioSystems Science and Engineering (IISc), Bengaluru, attempt to understand specific biomarkers and the immune environment. They aimed to predict how patients with solid tumours would respond to immune checkpoint blockade (ICB) therapies.