Novel role of FOXO, a transcription factor, in egg cell development
Banya Kar
A recent study by researchers at the National Institute of Immunology (NII), New Delhi, led by Arnab Mukhopadhyay, used C. elegans to show how damage to somatic tissues in the body can influence the development of reproductive cells—particularly eggs. They found that DNA damage signals from uterine tissue can stop egg cell formation through a key FOXO transcription factor, which is a highly conserved protein across different organisms.
