A new study by researchers at the Indian Institute of Technology, Kanpur has identified a small molecule drug which shows therapeutic promise against Huntington's disease, a fatal neurodegenerative disorder. The molecule prevents the formation of protein clumps or aggregates which are detrimental for the health of neurons.
A recurring challenge for combination cancer therapy has been delivering drugs with widely differing properties to the tumour site. Now, researchers at the Regional Centre for Biotechnology, Faridabad, and Amity University, Haryana, have come up with a novel strategy for combining three different drugs into a single package that can induce tumour shrinkage when injected.
The Hemidactylus geckos have evolved into several distinct species in the Indian peninsula, some of which often show up as uninvited guests in our houses. Researchers at the Center for Ecological Sciences, Indian Institute of Science (CES-IISc) have shown that differences in morphology among species of ground-dwelling geckos can indicate changes in the past climate of peninsular India.
Lead is a heavy metal that was once used extensively in paints, gasoline, batteries, plumbing etc. Now, a new study by Indian researchers shows that in addition to its many known toxic effects, lead may lower immunity as well. Through a series of experiments on fruit flies, the researchers have demonstrated a link between lead exposure and susceptibility towards bacterial infections.
Researchers at the National Center for Biological Sciences (NCBS), Bengaluru have used a combination of techniques to unravel the mystery of how prions misfold. Prions are proteins that undergo structural changes to form compound assemblies called amyloid fibrils, which can lead to fatal infectious neurodegenerative diseases like the Mad Cow disease and other Transmissible Spongiform Encelopathies in mammals.
Uncontrolled blood loss following an accident or injury can pose severe risks to the health and life of the patient. Now, a team of Indian researchers from the Institute of Nano Science and Technology have developed a novel environment-friendly microparticle which can stop bleeding quickly if applied to the injury site.
Researchers from the Centre for Climate Studies, Sathyabama Institute of Science and Technology, Chennai, have discovered that the accumulation of chromium (a heavy metal) and low salinity might have caused mass death of fish in the Adyar estuary in Tamil Nadu in 2017.