The 6th National Post-Doc Symposium (NPDS), took place from October 12 to 14, 2023, at the Trivedi School of BioSciences, Ashoka University, Sonipat. It was organised by the Early Career Researchers at the National Centre for Biological Sciences, Institute for Stem Cell Science and Regenerative Medicine, and Ashoka University, with support from IndiaBioscience.
A team of researchers at the SRM Institute of Science and Technology, Chennai, identified a natural compound, cordycepin, to be protective against cadmium-induced toxicity in zebrafish. They found that cordycepin alleviates the gut inflammation, tissue damage, and developmental deficits caused by cadmium exposure in zebrafish. This work holds therapeutic potential for cordycepin in treating cadmium-induced toxicity.
Candida infections, caused by pathogenic fungi, pose a significant threat, especially to vulnerable individuals. Researchers from Regional Centre for Biotechnology, Faridabad, Indian Institute of Technology Delhi, Gautam Buddha University, Greater Noida, have developed a gelatin-based platform that closely mimics human skin, aiding in the study of Candida biofilm formation and potentially speeding up drug development to combat these infections.
A team of researchers at the Regional Centre for Biotechnology (RCB), Faridabad created a mouse model with a deleted MYH3 gene to study congenital musculoskeletal disorders. They found that the loss of this gene led to traits resembling spondylocarpotarsal synostosis syndrome (SCTS) in adult mice, shedding light on MYH3-associated conditions. This work holds promise for understanding rare genetic disorders.
A collaborative study from the Indian Institute of Science, Bangalore, and other institutes, found that agamid lizards display rapid colour change in different contexts, including thermoregulation, communication, and stress. The massive range of colours in these species opens up new questions on the whys, hows, and whens of this colour change.
A team of researchers from Indian Institute of Science Education and Research (IISER) Kolkata and IISER Pune engineered a lipopeptide-based siRNA transporter, ensuring that siRNAs could efficiently enter the cytoplasm of the cells in functional form and perform gene silencing.
A research group working on packaging antitumour drugs from Regional Centre for Biotechnology, Faridabad, and Amity University, Haryana, has successfully trained immune cells to attack tumour cells. They have developed a hydrogel-based anticancer drug delivery system that reduces toxicity and targets tumours directly. This innovation shows promise for more effective cancer treatment pending further research and clinical trials.