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Unseen foundations of brain health: How blood vessel damage may trigger Alzheimer’s disease, Amyotrophic Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD)

Ashok Cheemala

The brain, a biological engineering wonder, depends on a delicately balanced system of cells, signals, and defense barriers to work in harmony. For decades, researchers have studied neurodegenerative diseases like Alzheimer’s disease, Amyotrophic Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD) with a near-exclusive focus on neurons, the brain’s information processors. However, what if the earliest signs of damage occur not within neurons, but in the blood vessels that support and protect them?

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