Venture Center is seeking a highly motivated Biotechnology Engineer (PhD preferred) with 0 – 2 years of relevant experience in microbial bioprocessing. The ideal candidate should demonstrate hands-on expertise in handling bacterial, yeast, actinomycete, and fungal strains, and must be proficient in operating bench-top fermenters (1 L to 100 L). The role involves end-to-end responsibility for fermentation studies — including inoculum preparation, bioreactor operations in batch/fed-batch/continuous modes, scale-up studies, downstream processing, and associated analytical work.

• Independently handle microbial cultures (bacteria, yeast, actinomycetes, fungi) from shake flask to fermenter scale.
• Perform inoculum preparation, fermentation runs (batch, fed-batch, continuous), and monitor critical process parameters.
• Operate and troubleshoot bench-top fermenters ranging from 1 L to 100 L.
• Execute scale-up studies and support technology transfer activities.
• Ensure compliance with CIP (Clean-in-Place) and SIP (Sterilization-in-Place) protocols for fermenters.
• Participate in downstream processing, including recovery and purification of target molecules.
• Conduct biochemical and analytical assays such as sugar profiling, amino acid profiling, fatty acids/​fatty alcohols estimation, protein quantification, SDS-PAGE, and related methods.
• Perform analytical method development for novel molecules or bioprocess intermediates.
• Document experimental protocols, batch records, and technical reports accurately.
• Adhere to safety standards, GLP/GMP practices, and organizational quality systems.
• Collaborate with cross-functional teams including process engineering, analytical sciences, and product development.

This role offers significant exposure to end-to-end bioprocess development, scale-up operations, and translational research. The candidate will gain opportunities to grow into leadership roles in Process Development, Scale-up Engineering, or Manufacturing Operations within the organization.

• M.Tech in Biotechnology, Bioprocess Engineering, Microbiology, or related field.
• PhD in Biotechnology/​related discipline preferred.

• 0 – 2 years of relevant experience in microbial fermentation and downstream processing (academic or industry).
• Proficiency in microbial strain handling (bacteria, yeast, actinomycete, fungi).
• Hands-on experience with fermenters (1 – 100 L), including CIP & SIP operations.
• Knowledge of fermentation modes: batch, fed-batch, continuous.
• Basic understanding of downstream processing techniques.
• Familiarity with analytical methods: sugar analysis, biopolymer assays, fatty acid/​fatty alcohol profiling, amino acid analysis, protein characterization, SDS-PAGE.
• Ability to develop and validate analytical methods.
• Behavioral Competencies:

1. Strong problem-solving and analytical skills.
2. Attention to detail with strong documentation practices.
3. Team player with effective communication skills.
4. Willingness to learn, adapt, and contribute in a start-up/scale-up environment.

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