Advanced multi-omics technologies provide revolutionary strategies to study complex biological processes, e.g. to systematically decipher biosynthetic pathways to mechanistically challenging, structurally complex, widely used plant medicinals that cannot be economically synthesized. A multi-omics strategy is proposed to deduce biosynthetic pathway to rohitukine, a chromone alkaloid, widely used in cancer treatment. Distinct cell types involved in plantawill be identified using mass spectrometry based metabolite imaging in situand laser microscope dissection. Knowledge gained can be applied to developing synthetic biology approaches in order to obtain new sources of these compounds in other host systems.

One year contract, extendable up to next two years based on performance.

As per SERB, DST norms

• Molecular and biochemical techniques
• Isolation, purification and structural characterization of secondary metabolitesExperience in Chromatographic techniques like HPLC, GCMS and LCMS
• Experience in RNA isolation, Synthesis of cDNA. PCR, RT-PCR, qPCR, cloning and transformation. 
• Bioinformatics: transcriptome analysis 

Send out the detailed CV on or before the last date – 29.04.2019. All selected candidates will be informed. No TA/DA will be provided. Interested candidates to send their cv to mohan.​kumar@​tdu.​edu.​in