ANRF-funded role investigating locus coeruleus norepinephrine dynamics in synaptic plasticity

The Jain Lab at CHINTA, TCG CREST (Kolkata, India) invites applications for a postdoctoral researcher to study behavioural timescale synaptic plasticity in CA1 neurons, with a focus on sex-specific differences in locus coeruleus (LC)-mediated norepinephrine signalling. This project integrates patch clamp electrophysiology, optogenetics, and two-photon imaging to dissect LC-CA1 circuit mechanisms in vivo.

More details about the Jain lab can be found here: https://​sites​.google​.com/​view/…

Resources: Access to cutting-edge facilities, including two-photon microscopes and optogenetic setups.

Scope

• Investigate how LC norepinephrine release drives synaptic plasticity during learning tasks.
• Compare plasticity dynamics between male and female models.
• Develop novel experimental paradigms combining optogenetic LC stimulation and two-photon calcium imaging.

Techniques: Hands-on training in slice electrophysiology, in vivo imaging, and behavioral assays.

Collaboration: Opportunities to work with computational neuroscientists and molecular biology teams.

Initial 2‑year contract, extendable based on performance.

Competent Salary with experience.

PhD (or near completion) in neuroscience, physiology, or related fields.

• Experience in electrophysiology or optical imaging; willingness to learn new methods.
• Strong analytical skills (Python/​MATLAB preferred).

Preferred:

• Background in synaptic plasticity, neuromodulation, or sex differences research.
• Familiarity with stereotaxic surgery or rodent behaviour assays.

Interested candidates can send their CV, 1‑page research statement, and 2 references to Dr. Anant Jain at anant.jain[at]tcgcrest​.org with the subject line​“ANRF Postdoc Application – [Your Name]” 

And the applications for this are accepted on a rolling basis with no deadline, the position will be filled when there is an appropriate candidate.