Applications are invited from Indian citizens for a Research Associate position in the DBT sponsored project.

The project aims to investigate for the first time the nexus between a membrane channel protein (CLIC1) and a chaperone (Gankyrin) in cancer cell migration and invasion using an integrated approach encompassing tools in biophysics, biochemistry, cell biology, chemical biology, synthetic chemistry, structure-based inhibitor design, small molecule screening and computational methods for development of peptide or small molecule-based CLIC1 inhibitors for therapy.

In this multidisciplinary and multi institutional project the selected candidate will be responsible for understanding the transcriptomic and proteomic changes responsible for cancer cell migration driven by protein-protein interactions involving CLIC1 and Gankyrin.

Initially for 6 months. Depending on satisfactory performance the position will be extended for another two and half years.

Salary will be between Research Associate I — Research Associate II

ACTREC is looking for motivated and enthusiastic PhD degree holders in life science and allied subjects with expertise in mammalian cell culture, protein chemistry, molecular biology and cell biology techniques including skills required for characterizing protein interactions such as immunoprecipitation.. Knowledge in protein structure, folding and conformation is desirable. Those awaiting their degree but have submitted their thesis are eligible to apply. The candidate must have at least one peer reviewed publication in the area of expertise and must be able to think and work independently as well as in collaboration.

The selected candidate will be interacting with investigators from IISER Bhopal, IISER Pune, IIT Mumbai to develop hypothesis and characterize the mechanism of cellular migration in the context of select PPI.

Eligible candidates may apply and send their CV and educational documents in a pdf format to dd_​cri@​actrec.​gov.​in Application should contain the subject “ Application for Research Associate”. The application should include a cover letter supporting their candidature.

The last date of application is 23^rd December 2023 till 3:00 PM.

Only the short-listed candidates will be contacted by email and notified about the interview date and timings.

The interview will be conducted in person. If the candidate is unable to attend in person they can write to projectstaff@​actrec.​gov.​in for online access.

The selected candidate will work in Dr Prasanna Lab, Protein interactome lab for structural and functional Biology, ACTREC https://​prasan​nal​ab​.wixsite​.co…