The rapidly increasing susceptibility of antibiotics in controlling bacterial infections has paved the way for the development and use of alternative therapies to treat bacterial infections to reduce the burden on antibiotics. One of the better alternative therapies to combat bacterial infections is Phage therapy. The bacteria-eating viruses (Bacteriophages) coevolved as a nemesis to bacteria during the course of evolution and the process still can be witnessed in action. The phages evolved in a very specific way, by gaining the ability of selective and strain-specific action to combat bacteria, proving their usefulness in treating infections involving MDR as well as XDR bacterial infections