Biomedical optics has become one of the most inevitable field in the recent research in clinical diagnosis and treatment. In this course, we will learn about the fundamentals of biomedical optics, starting from how the photon interacts with a single atom, to a diatomic species, and then with polyatomic species such as haemoglobin. You will learn the basics of spectroscopy and different imaging modalities such as fluorescence, UV-Vis-NIR, diffuse optics, polarization, Speckle contrast, and multimodal imaging. You will also learn about fundamental and advances in the field of optical biosensors and various plasmonic resonances. We will also discuss the principles and details along with demonstration of various microscopic imaging such as brightfield, phase contrast, fluorescence and polarization-based microscopy.