Aging leads to dysregulation of bone marrow mesenchymal stromal cells (MSCs) which in turn causes hematopoietic stem cell (HSC) dysfunction and increased production of myeloid cells. In this context, defects in beta adrenoreceptor (β‑AR) signaling in MSCs is known to cause HSC dysfunction in aging. The Research Scholar will be involved in delineating the molecular mechanism underlying MSC dysregulation during aging using gene cloning, molecular biology and immunology techniques in animal cell lines and primary cell cultures.

Location: Centre for Life Sciences at Mahindra University which has major focus in research undertaken by faculty trained in modern technologies such as personalized medicine, genome editing, metabolic engineering, immunobiology, host-pathogen interaction, GMOs, molecular diagnostics, nanobiotechnology, bioprocess modelling, biosensors, green products, stem cells & regenerative medicine, biomaterials, biomedical devices, computational biology, clinical informatics, etc.

Key Responsibilities:

• Maintenance, stimulations and assays using animal cell lines
• Establishment of mouse bone marrow-derived MSC cultures
• Gene cloning and generation of knock out cell lines
• Performing qRT-PCR, ELISA, Western blotting etc.
• Data analysis, data compilation and manuscript writing

The position is for 1 year. The candidate will have the opportunity to register in PhD programme at Mahindra University.

Rs. 31,000/ month plus free lodging and boarding on campus.

Master’s in Science degree holders in any field of Biology and Biotechnology.

• Proficiency in molecular biology and immunology techniques
• Hands-on training in gene cloning
• Experience in animal cell culture

Interested candidates are invited to e‑mail their applications, which should include a CV, the names and contact information of at least 2 referees, and a cover letter to Dr. Pijus K. Barman (pijus.​barman@​mahindrauniversity.​edu.​in) via email. Please use the subject line ​“JRF Application – Centre for Life Sciences”.