Humane Society International (HSI) and its affiliates together constitute the world’s largest force for animal protection, working lawfully and professionally, building relationships with government authorities and elected officials, business leaders and other decision-makers to identify and implement workable solutions to animal welfare concerns. HSI/India was formally incorporated in 2012, and today works toward eradicating rabies through humane street dog population management, capacity building for Indian animal welfare organizations, strengthening farm animal and wildlife protections and ending animal testing. In partnership with HSI’s global team of scientists and policy experts, we advocate for an accelerated transition to a “21st century” paradigm in toxicology and health research based on human biology-based, non-animal tools and technologies.