The Institute of Bioinformatics is a not-for-profit organization engaged in research in Bioinformatics. This institute is located in Bangalore, India and was established in May 2002. Bangalore is a prime center for research and development and is the hub of information technology in India. The Institute of Bioinformatics emphasizes cutting edge research in Databases, Computational Genomics, Proteomics and Comparative Genomics. The initial goal of this Institute was to create a freely available Human Protein Reference Database using open source technologies and to experimentally verify predicted human genes using molecular biology and proteomics-based methods.