Applications are invited for the post of Research Scientist — 1 – DMPK at the Foundation for Neglected Disease Research at Bengaluru.

Foundation for Neglected Disease Research (FNDR) is a unique not-for-profit R&D organization dedicated to developing novel therapeutics, diagnostics and devices for diseases with a high socio- economic impact.

Roles and Responsibilities:

The key responsibility of the candidate will be to perform and analyze in vitro and in vivo DMPK studies to support drug discovery and development projects. The candidate will be involved in planning, designing and set-up of DMPK experiments, handling instruments, maintaining the laboratory and preparing and reviewing the protocol. He/​she will also be responsible for writing reports and communicating with the project team and presenting DMPK data in the project meetings.

Technical Skills

• Ability to set up and perform physiochemical assays such as solubility and logP
• Experience in conducting in vitro DMPK assays, including microsomal and hepatocyte stability, plasma stability, CYP inhibition, and blood/​plasma ratio Skilled in the development and validation of bioanalytical methods across various biological matrices Experience in analysis of in-vivo pharmacokinetic samples
• Knowledge of sample processing techniques such as protein precipitation, liquid-liquid extraction, and solid-phase extraction
• Proficient in handling LC-MS/MS for quantitative analysis Experience in protocol preparation and report writing Presentation of DMPK data in scientific team meetings

Additional:

• Experience in animal handling and conducting pharmacokinetic (PK) studies skilled in maintaining and working with cell lines such as Caco-2Ability to interpret pharmacokinetic data using Phoenix WinNonlin
• Experience in working in a GLP or GLP-like environment

Basic Skills required

• Ability to work independently with enthusiasm and self-motivation
• Strong decision-making and problem-solving skills
• Effective collaboration and teamwork across multidisciplinary functions
• Knowledge of drug discovery and development processes
• Excellent oral, written, and interpersonal communication skills, with proficiency in English
• Proficient in computer applications including word processing, spreadsheets, and presentation tools 

Other Information

• Candidate must be an India citizen

Salary will be commensurate with experience.

M.Pharm or MS (Pharm) or PhD

Industry experience of 2 to 5 years

Interested candidates to share their resume at hr@​fndr.​in citing *Application for Research Scientist 1 ‑DMPK* in the subject line and notice period, current location, current and expected CTC in the body text.