The annual Young Investigators’ Meeting (YIM) brings together exceptional young and senior scientists, heads of institutions, and representatives from funding agencies for interactions focusing on science careers, mentoring and networking. The program features illuminating talks by renowned scientists, posters, and panel discussions that focus on a wide variety of topics, including choosing the right research problem, translational research, personnel management, funding opportunities and mentorship. Senior scientists describe their scientific journeys, sharing inspirational and amusing anecdotes about their experiences with younger scientists who are establishing their careers.