After ten successful years of Young Investigators Meetings (YIM) – national meetings organized by IndiaBioscience to bring together early career life science researchers from all over India to network, share best practices or challenges, and build collaborations – erupted the need to have local scientific networks within India’s major cities. Researchers in Hyderabad led the initiative with the first ever Regional Young Investigators Meeting – RYIM 2018, in which they were supported by IndiaBioscience.

The meeting was held on 18^th-19^th August, 2018, at the School of Life Sciences, University of Hyderabad (UoH). It focused on bringing together academicians, industries and start-ups together on one platform with an aim to Congregate – Collate – Collaborate. “If you are active in science, you are young enough to be in the meeting”, said Bindu Madhava Reddy, Assistant Professor at UoH and one of the 7 co-organizers of the meeting from different research/research-enabling organizations in the city.

The meeting was attended by roughly 100 registered participants from 16 academic institutes (including 3 undergraduate educators), 3 clinical research institutes, 4 science/research/discovery promoters, 16 representatives from industry and start-ups, and 2 freelance scientists. 6 of the attending institutes showcased their infrastructure available for use to outsiders to maximise utilization. The diversity in interests and affiliations of the attendees provided a fertile ground for seeking collaborations in exploratory as well as translational research. Via its ‘breakout sessions’ the meeting also enabled assemblages of expertise and interests with the hope of facilitating large scale collaborative research projects in the city.

G Padmanaban, former director and now honorary professor at the Indian Institute of Science (IISc), Bangalore, set the tone of the meeting in his inaugural talk, advising the attendees to build collaborative mega projects among scientists in the city leveraging each other’s strengths. D Balasubramanian, former research director and now distinguished scientist at the LV Prasad Eye Institute (LVPEI), emphasized the need for more openness regarding infrastructural facilities available in the city, beginning with the institutes represented in the meeting.

The keynote speaker, Muralidhar Kambadur, Jawaharlal Nehru Chair Professor at School of Life Sciences, UoH, laid paramount importance on prioritizing high quality original research. He pointed out that as bandwagon research and the need to publish in certain journals has taken over science, the focus has shifted to infrastructure rather than originality of the idea. Unlike other scientific fields in India, he says, life science researchers have focused on procuring but not building their own infrastructure – an aspect that proves quite expensive in the current scenario. He strongly suggested that the community should now shift focus from capacity building in techniques to nurturing originality of ideas.

Educators are indispensable if such a shift in mind-set has to happen. The educators present at the meeting discussed the need of educational content that the undergraduate students in the city can understand and relate to better. They also pointed out the lack of clarity among young students about different opportunities that emerge from a training in science. These discussions highlighted a need for consolidating the different school and college science outreach and teacher training programs running in the city, and strengthening them as a community.

The meeting also included a panel discussion with administrators from eminent educational, research and research-enabling organizations in Hyderabad. Panellists included Appa Rao Podile, Vice Chancellor, UoH, Rakesh Mishra, Director, CSIR - Centre for Cellular and Molecular Biology, Debashish Mitra, Director, Centre for DNA Fingerprinting and Diagnostics, Reddanna Pallu, President, Federation of Asian Biotech Association and professor at UoH, Subeer Majumdar, Director, National Institute of Animal Biotechnology, Shivaji Sisinthy, Director-Research, LVPEI, and Deepanwita Chattopadhyay, CEO, IKP Knowledge Park. The discussion was moderated by Uday Saxena, Chief Mentor, Dr Reddy’s Institute of Life Sciences.

Delays in procuring grant money even after it has been sanctioned is a common problem that academic researchers unanimously complain of. Touching upon this in the panel discussion, Mishra acknowledged the complexity of the problem and said it is the institute’s responsibility to keep aside funds to support a researcher in his/her initial five years to establish his/her lab without worrying about grants. An unequivocal gap between academia and industry was touched upon in the discussion. Mishra also emphasized the need for Indian academia to start seeking funds from industry for research. Chattopadhyay spoke on the disconnect between the two sectors due to lack of understanding of industry standards such as regulatory affairs and clinical trials among the academicians. Saxena wrapped up the discussion urging academicians to shed their shyness and be more proactive in discussing their ideas with industries. He suggested that academicians should rely on industries for judging an idea’s maturity to suit industry’s needs.

The meeting also focused on identifying gaps between academic research and translation. Multiple sessions were dedicated to discussing how to develop a conducive environment for translation and entrepreneurship in Indian cities. There were also discussions on understanding the need and procedure of patent filing better and the role of business developers and service providers in research institutes. Representatives from start-up enablers mentioned the need for scientists to mentor start-ups as subject matter experts.

As Ron Vale, professor at University of California, San Francisco, IndiaBioscience board member, and long-standing proponent of efficient scientific networking and collaboration, mentioned in his address to the attendees, this RYIM should catalyse a sense of leadership beyond the few days of the meeting. With Kolkata and Srinagar hosting two more RYIMs, Indian research space is coming of age with setting long-term goals and shared vision for the community, as well as working towards engaging various key stakeholders in education and industry more actively.

The tenth edition of Young Investigators’ Meeting (YIM) was held in Thiruvananthapuram from March 5 to March 8, 2018. Being the tenth year, this year’s YIM was structured on a different format and brought participants from all the previous YIMs under one roof for the entire duration of the meeting. The key feature of this year’s YIM were the four breakout sessions, where scientists debated on four themes– 1) Best practices for recruitment and mentoring of YIs in India, 2) Sharing resources and collaborations, 3) PhD and postdoctoral training in India and 4)Future of biology research in India.

The organisers for this year’s YIM were, Debasree Dutta of Rajiv Gandhi Centre for Biotechnology, Piyali Mukherjee of Presidency University, Sharmistha Banerjee of Hyderabad Central University and Smita Jain of IndiaBioscience

Day 1 @ YIM 2018: Setting the tone

The inaugural session at YIM 2018 started with an introductory talk by Satyajit Mayor, Director at NCBS and inStem. He spoke about the 10-year journey of YIMs and how it is great to be back in Thiruvananthapuram– the city that hosted the first YIM––for its decadal celebration. He urged young scientists to question if the science they practise is relevant to their context, adding that “ relevant science needn’t always be applied, basic science is relevant too.”

Mayor’s talk was followed by Ron Vale’s keynote lecture. Vale, a professor at University of California, San Francisco was on a sabbatical at NCBS Bangalore, when the idea of organising a YIM-like meeting, first occurred to him. In the 10 years hence, the meeting has gone from strength to strength and has helped build a connected community of Indian biologists. He insisted repeatedly that Indian biologists should steer clear of the ways in which research is practised in the US and instead create systems that allow research to thrive in India and draw focus on on societal challenges unique to India.

Second keynote was delivered by K VijayRaghavan of NCBS who was also recently nominated as the Principal Scientific Advisor to the Government of India. He said that science and technology are the solution to problems of scale that are abundant in India. He acknowledged the gap that divides politics and science in India and hoped that with better communication and ingenuity from scientists, this gap will be filled.

Day 2 @ YIM2018: Picking up steam

Day 2 at YIM began with a talk on the whys and hows of science outreach by L S Shashidhara of IISER, Pune. This was followed by a talk from Smita Jain of IndiaBioscience, who explained to the young researchers the various ways in which they can engage with the IndiaBioscience website. There were talks from young researchers working in areas of biology as diverse as molecular biology, biophysics, ecology and evolution.

However, the highlight of the day were the breakout sessions. The first session on– best practices for recruitment and mentoring of YIs in India. The participating scientists were divided into groups of 10 -12 and each group discussed the challenges in face of good recruitment practices and factors determining future promotions. The points discussed during this breakout session were compiled and presented to the audience by Thomas Pucadyil of IISER, Pune who was also the leader for this theme.The scientists were all in agreement that the recruitment process should be made more transparent and that a scientist’s success should not be measured in terms of number and impact factor of their publications.

The breakout session was followed by a special talk by Shinjini Bhatnagar of THSTI and Satyajit Rath of Agharkar Research Institute on bridging the gap between scientific evidence and policymaking.

In the second breakout session of the day, the young researchers split into groups again, to discuss how sharing resources and collaborations can improve science and what stops young scientists from collaborating. The researchers felt that it is often quite hard to assess a researcher’s contribution in a collaborative project and therefore a clearly defined methodology to assess researcher contribution is needed. There was a general consensus about promoting collaborations and that it should be encouraged even in younger researchers doing PhD or postdoc. There were also suggestions about setting up state of the art regional technical facilities that can be used by any researcher interested in doing so. The discussions on this theme were collated and presented by Roop Mallik of TIFR, Bombay who was the leader for this theme.

Day 3 @ YIM2018: Going full throttle

Day 3 saw a series of talks by young researchers on translatable research, tumour biology and plant defense mechanisms. A special session was organised to address challenges related to funding. This session started with a talk by Arabinda Mitra of DST. He spoke about the multiple international partnerships that the government has started and how these partnerships will allow for exchange of scientific ideas. There was another talk by Barbara Pauly of Human Frontier Science Program (HFSP)who said that her organisation is looking to fund bold and audacious projects in interdisciplinary science involving multi-country partnerships. A panel discussion was also organised to address the challenges faced by young researchers in getting funded. The panelists were, Meenakshi Munshi and Suman Govil of DBT, Arabinda Mitra of DST and Vandana Gambhir of IISER, Pune. The discussions were led and moderated by Shahid Jameel of India Alliance. Munshi insisted that scientists must follow the directives of their sanction orders diligently and initiate a dialogue with the funding agency in case of any problems. Right after the panel discussion was a talk by Savita Ayyar, who is a Research Management Consultant. She spoke about the Indian Research Management Initiative (IRMI) that she is developing in partnership with India Alliance, to help Indian research institutes put in place better practices of research management.

The focus for Day 3’s breakout session was PhD and postdoctoral training in India. Most participants agreed that the both PhD and postdoctoral training in India require some radical changes. Those doing PhD and Postdoc in India should be empowered, offered quality mentorship and made aware of the various kinds of job opportunities.The discussions on this theme were presented by the theme leader Sachin Kotak, who is from IISc.

Day 3 ended with a special talk by Subhash Lakhotia of BHU about the history and future biological research in India.

Day 4 @ YIM 2018: Ending on a high note

The fourth and last day of YIM started with talks from young investigators. It was followed by an impromptu session on women in science where young scientists discussed some of the problems faced by women scientists.

A panel discussion on effective science communication was also organised on the last day. The panelists for this session included, Dinakar Salunke of ICGEB, Dhrubajyoti Chattopadhyay of Amity University, Rakesh Mishra and Jyotsana Dhawan of CCMB and Shubha Tole of TIFR. The discussions were moderated by L S Shashidhara of IISER, Pune. All panelists agreed, that in communicating their science, scientists should not worry about the journal’s impact factor. "Instead think about the audience of the journal you are going to publish in. Choose a journal which is read by the people whom you would like to know about your work", suggested Salunke.Another important point discussed, was making use of pre-print archives. It helps avoid any authorship-related conflicts and also allows scientists to share and get feedback on their work from their colleagues.

For the breakout session was on Day 4, scientists discussed the future of biological sciences in India. Some facts that emerged from this breakout session were– universities should have better access to infrastructure, both applied and basic research should be encouraged, with curiosity being the main driver of research, young students should be free to study any combination of subjects as it will foster interdisciplinarity. The leader for this theme was Rashna Bhandari of CDFD.

The last discussion of the day was on the role of YIM and IndiaBioscience in the coming years. There was a unanimous consensus that YIMs should continue. There were also suggestions about what IndiaBioscience can do for the community, like creating an online database of PDFs looking for jobs, organising meetings for institute directors and organising sessions on industry-academia collaborations, science communication and patenting.

The discussions made way for the final event of the day, the poster session. Like all previous days, after the talks ended, the participants showcased their work via poster presentations. On each day, the poster arena saw the scientists engaging in many lively discussion, both formal and informal.

For most participants the breakout sessions and the opportunity to network with their peers was the best part of the meeting. Plans for regional chapters of YIM were made and the outcomes from each breakout session are being compiled into white papers.