Scientists at the National Institute of Science Education and Research (NISER), Bhubaneswar, have uncovered the molecular mechanism behind Gram-negative bacteria’s resistance to the drug PC190723, revealing how intra-molecular interactions in proteins, such as salt bridges, prevent the drug from binding effectively.

Researchers at the Tata Institute of Fundamental Research (TIFR) Mumbai, have recently elucidated the neurocircuit mechanism of DOI (2,5‑dimethoxy-4-iodoamphetamine), a serotonergic psychedelic known to reduce anxiety. Their findings pave the way for emerging clinical research and potential therapeutic interventions targeting mental distress caused by anxiety.

Researchers at Jadavpur University, have developed a mathematical model that can predict the way psoriasis progresses during treatment, provide optimal treatment solutions and also calculate any future triggers.

Researchers, led by Sunil Laxman, Institute for Stem Cell Science and Regenerative Medicine, Bengaluru, have experimentally shown that cells follow principles of economics when they encounter nutrient limitation. Their results provide an economic framework for prioritisation strategies used by cells on facing nutrient limitation.

The first Regional Young Investigators’ Meeting (RYIM)of the 2024-2025 took place in Visakhapatnam, bringing together academia and industry to foster biomedical innovation. Hosted by GITAM Deemed to be University (GITAM) and Andhra Pradesh MedTech Zone Pvt. Ltd. (AMTZ), the event featured insightful workshops, networking sessions, and discussions on bridging the gap between research and medical technology development.

In its 5th edition, the IndiaBioscience Outreach Grants (IOG) has been awarded to grassroot ideas addressing niche problems. Five teams have been awarded the grant for the first time and one team has received an extension grant. Read the article to know more about the 5th IOG awardees' projects.

Researchers from Indian Institute of Technology, Guwahati, have developed the Human Physiomimetic Liver Acinus Model (HPLAM), a 3D-printed liver model that mimics human liver functions to better predict drug-induced liver injuries. This advanced model aims to address the limitations of animal testing in drug toxicity evaluation, offering a more accurate and human-relevant alternative.