Salmonella typhimurium is a pathogenic bacterium that causes food-borne infections in humans. Researchers from the Regional Centre for Biotechnology, Faridabad, find that Salmonella globally alters a post-translational protein modification called Sumoylation in infected cells and manipulates the host cell’s intracellular transport machinery.
Plasmodium, the malaria parasite, is believed to be of simian origin. Non-human primates can act as a reservoir for this parasite, and in certain cases the parasite has been shown to be transmissible between humans and apes. Researchers led by Praveen Karanth from the Indian Institute of Science, Bengaluru recently profiled Plasmodium in multiple Indian non-human primate species, in an effort to better understand the spread of this parasite in monkey populations.
Several lines of evidence suggest that males and females differ in their biological response to stressful situations. A new study from researchers at IICT and CCMB, Hyderabad, explores one mechanism for this, demonstrating that the heterochromatin region of the Y-chromosome may contribute to the regulation of anxiety-like behaviour and stress response in male mice.
Researchers from the University of Mysore have recently found that an enzyme extracted from the leaves of a medicinal plant, Tricosanthus tricuspidata, can counter the tissue damage caused by the bite of the venomous saw-scaled viper. This is the first scientific report of the anti-snake venom properties of this plant, which is known to be used by local tribal communities to treat snakebites.
In order to treat severe burn wounds, the progress of healing needs to be monitored regularly. This is usually done by measuring collagen levels using biochemical or histopathological methods. Now, researchers from the Manipal Academy of Higher Education, Manipal, have come up with a way to assess burn wound healing by using a minimally-invasive laser-based method to optically measure collagen.
A recent large-scale study of almost four thousand Indian children found the prevalence of neurodevelopmental disorders to be nearly 12%. During the course of the study, the authors identified, developed and validated diagnostic tools for several of these disorders in the Indian context and have now made them available in the public domain for anyone to use.
Artificial light at night has become a staple part of city-living and is quickly encroaching into rural regions as well. Vinod Kumar's group at the IndoUS Center for Biological Timing, University of Delhi recently discovered that exposure to bright lights at night can affect the parts of the brain involved in mood and cognition and lead to depression-like symptoms, by using Indian crows as a model system.