Candida infections, caused by pathogenic fungi, pose a significant threat, especially to vulnerable individuals. Researchers from Regional Centre for Biotechnology, Faridabad, Indian Institute of Technology Delhi, Gautam Buddha University, Greater Noida, have developed a gelatin-based platform that closely mimics human skin, aiding in the study of Candida biofilm formation and potentially speeding up drug development to combat these infections.
A team of researchers from the Indian Institute of Science, Bengaluru has explored a new approach to treat mycobacterial infections, which are becoming increasingly drug-resistant. They found that a cocktail of mycobacteriophages – viruses that infect mycobacteria but not humans– were effective against slow- and fast-growing mycobacteria, in cultures. This has clinical significance in treating tuberculosis (caused by M.tuberculosis, a slow-growing mycobacterium), which is of concern, especially in developing countries. In this article, Edna George reports on this recent study by Rachit Agarwal’s team.
The tuberculosis bacteria is notorious for its ability to stay dormant for years within the human body, evading the immune system and always one step away from causing aggressive infection. Now, a study from researchers at Translational Health Science and Technology Institute (THSTI), Faridabad, and Institute of Microbial Technology (IMTech), Chandigarh, has investigated a novel molecular pathway that helps the bacteria avoid the notice of the immune system.
Tuberculosis is a common comorbidity in those infected with HIV/AIDS, and the two conditions are known to exacerbate one another. A new study from researchers at the Indian Institute of Science, Bengaluru demonstrates that Mycobacterium tuberculosis, the tuberculosis bacteria, can reactivate dormant HIV within the human body, a process that can potentially be targeted by specific drugs.
The gut microbiome of wild animals can provide a plethora of information related to animal health. However, studies looking at evolutionary and animal health-related issues through the lens of gut microbes are currently lacking in India. A recent study reveals the gut bacterial diversity of Indian Gaur and its domesticated form Mithun.
A new collaborative study by researchers at University of Calcutta and University of Kalyani has found that a close symbiotic relationship between three species - a plant, a fungus, and bacteria - can be harnessed to promote the growth of rice plants by allowing them to take up more nitrogen from the environment.