Maternal health is one of the major thrusts of India's healthcare strategy moving into the next decade, and new research has been shedding light onto important problems that need to be addressed in this sector. One of these is Gestational Diabetes Mellitus, a condition which can increase the risk of metabolic disorders for the newborn as well as the mother. A study by the Diabetes in Pregnancy Study group India recommends a simple screening procedure to help identify such patients and provide them with the necessary care.
One of the reasons why viral infections can be difficult to treat is the high mutation rate displayed by many viruses, which can sometimes allow them to evade our immune systems and develop resistance to drugs. In this article, Shivani looks into the evidence gathered by scientists around the world on mutations in the genome of SARS-CoV-2, the virus that causes COVID-19.
The COVID-19 pandemic has set off a wave of research activities across the world, aimed at finding clues that would allow us to design effective therapeutics and vaccines. In one such effort, a team of researchers from the Indian Institute of Technology, Kanpur, have initiated a study into the molecular dynamics of the process via which the novel coronavirus attaches to cells of the human respiratory system.
Complex neurodegenerative disorders present a challenge to researchers who attempt to study them using model systems in the lab. Precisely measuring the behavioural defects which are hallmarks of such diseases in model organisms like the fruitfly can be difficult. Now, a team of researchers have come up with a new assay which can help assess movement-related impairments in fly models of Parkinson's disease.
Tuberculosis is an infectious disease that kills lakhs of Indians every year. Early detection of the disease is key to administering treatment; however, this has been hampered by the fact that current diagnostic techniques are often costly and time-consuming. Now, researchers from the Indian Institute of Science, Bengaluru, have come up with an inexpensive paper-based diagnostic device for tuberculosis detection.
As the problem of antibiotic resistance mounts worldwide, there is a pressing need for identifying and testing novel drug targets. Recently, a team of researchers from the Indian Institute of Science Education and Research (IISER), Pune, and the Central Drug Research Institute (CSIR-CDRI), Lucknow, has identified a protein pathway in an antibiotic-resistant bacterial strain which can be targeted using a small molecule to effectively kill the bacteria.
A new study by researchers at the Indian Institute of Technology, Kanpur has identified a small molecule drug which shows therapeutic promise against Huntington's disease, a fatal neurodegenerative disorder. The molecule prevents the formation of protein clumps or aggregates which are detrimental for the health of neurons.