A team of researchers from the National Institute of Immunology, New Delhi, Indian Institute of Technology Delhi, New Delhi, All India Institute of Medical Sciences, New Delhi, and Agency for Science, Technology and Research (A*STAR), Singapore, has revealed how crosstalk between two molecular pathways in the cells of the gut mediates the aberrant inflammation in Inflammatory Bowel Disease.
Foetal bovine serum is a nutrient-rich additive widely used for in vitro cell culture studies. However, harvesting the serum involves inhuman methods, calling for replacing or reducing its use in experiments. Here is a report on one such ethical step by a team of researchers who found a novel technique to grow skin cells by drastically reducing bovine serum use.
Timely intervention is critical to curbing the spread of vector-borne diseases like malaria. A team of researchers from Mangaluru, Karnataka, has shown that information technology tools such as their Malaria Control System can be powerful allies in anti-malaria programs. Here is a report on how digitisation helped Mangaluru chalk its success story against malaria.
As the world focused on developing coronavirus vaccines, a team of researchers from the National Brain Research Centre (NBRC), Manesar, delved into finding a therapeutic route for COVID-19. They tapped into the rich repository of Ayurvedic herbs and found Mulethi to be a promising candidate. The herb contains an active ingredient that shows potential in alleviating aggressive symptoms of COVID-19. Here is a report on their findings.
The tuberculosis bacteria is notorious for its ability to stay dormant for years within the human body, evading the immune system and always one step away from causing aggressive infection. Now, a study from researchers at Translational Health Science and Technology Institute (THSTI), Faridabad, and Institute of Microbial Technology (IMTech), Chandigarh, has investigated a novel molecular pathway that helps the bacteria avoid the notice of the immune system.
Tuberculosis is a common comorbidity in those infected with HIV/AIDS, and the two conditions are known to exacerbate one another. A new study from researchers at the Indian Institute of Science, Bengaluru demonstrates that Mycobacterium tuberculosis, the tuberculosis bacteria, can reactivate dormant HIV within the human body, a process that can potentially be targeted by specific drugs.
One of the main challenges in cancer chemotherapy is how to selectively kill tumour cells while leaving healthy cells alive. Researchers at the Indian Institute of Science Education and Research (IISER) Pune have come up with a novel approach where they use an artificially constructed ion channel and certain biochemical peculiarities of cancer cells to induce cell death in a highly targeted manner.