Tuberculosis is a common comorbidity in those infected with HIV/AIDS, and the two conditions are known to exacerbate one another. A new study from researchers at the Indian Institute of Science, Bengaluru demonstrates that Mycobacterium tuberculosis, the tuberculosis bacteria, can reactivate dormant HIV within the human body, a process that can potentially be targeted by specific drugs.
One of the main challenges in cancer chemotherapy is how to selectively kill tumour cells while leaving healthy cells alive. Researchers at the Indian Institute of Science Education and Research (IISER) Pune have come up with a novel approach where they use an artificially constructed ion channel and certain biochemical peculiarities of cancer cells to induce cell death in a highly targeted manner.
Early diagnosis is critical for the effective treatment of cancer and there has been a strong push for non-invasive and rapid techniques to detect malignant cells. In a new study, researchers from S N Bose National Centre for Basic Sciences, Saha Institute of Nuclear Physics, and Bose Institute, Kolkata have come up with a method to identify colon cancer cells using a biomarker that can be detected in low levels in bodily fluids.
Genetic variations and diversity both within and between populations play an important role in human health and disease. The Indo-US workshop on Human Diversity and Health Disparities brought together researchers from several different fields to discuss the importance of this often-neglected dimension in public health and biomedical research.
Maternal health is one of the major thrusts of India's healthcare strategy moving into the next decade, and new research has been shedding light onto important problems that need to be addressed in this sector. One of these is Gestational Diabetes Mellitus, a condition which can increase the risk of metabolic disorders for the newborn as well as the mother. A study by the Diabetes in Pregnancy Study group India recommends a simple screening procedure to help identify such patients and provide them with the necessary care.
One of the reasons why viral infections can be difficult to treat is the high mutation rate displayed by many viruses, which can sometimes allow them to evade our immune systems and develop resistance to drugs. In this article, Shivani looks into the evidence gathered by scientists around the world on mutations in the genome of SARS-CoV-2, the virus that causes COVID-19.
The COVID-19 pandemic has set off a wave of research activities across the world, aimed at finding clues that would allow us to design effective therapeutics and vaccines. In one such effort, a team of researchers from the Indian Institute of Technology, Kanpur, have initiated a study into the molecular dynamics of the process via which the novel coronavirus attaches to cells of the human respiratory system.