Plasmodium, the malaria parasite, is believed to be of simian origin. Non-human primates can act as a reservoir for this parasite, and in certain cases the parasite has been shown to be transmissible between humans and apes. Researchers led by Praveen Karanth from the Indian Institute of Science, Bengaluru recently profiled Plasmodium in multiple Indian non-human primate species, in an effort to better understand the spread of this parasite in monkey populations.
The gut microbiome plays a critical role in regulating human metabolism and health. Bug Speaks, a new initiative by the bioinformatics company Leucine Rich Bio, aims to utilize information gleaned from assessing the gut microbiome to predict disease susceptibility and provide personalized health recommendations.
In order to treat severe burn wounds, the progress of healing needs to be monitored regularly. This is usually done by measuring collagen levels using biochemical or histopathological methods. Now, researchers from the Manipal Academy of Higher Education, Manipal, have come up with a way to assess burn wound healing by using a minimally-invasive laser-based method to optically measure collagen.
A recent large-scale study of almost four thousand Indian children found the prevalence of neurodevelopmental disorders to be nearly 12%. During the course of the study, the authors identified, developed and validated diagnostic tools for several of these disorders in the Indian context and have now made them available in the public domain for anyone to use.
The last two hundred years have seen seven cholera pandemics and multiple regional outbreaks. Now, a new study from researchers at Vidyasagar University, West Bengal, explores how Vibrio cholerae, the comma-shaped bacterium which causes cholera, uses flagella and quorum sensing mechanisms to survive and form biofilms, which increase disease spread and enhance the potential for epidemics.
Nephrotic syndrome is one of the most common kidney disorders in children, and a large proportion of patients prove resistant to the classical mode of treatment - steroids. In a new collaborative study spanning across continents, researchers have identified six novel genes involved in the pathogenesis of this disorder.
Pancreatic cancer is one of the deadliest forms of cancer, usually detected in the late stages and almost always fatal in consequence. Now, a new study suggests that fingolimod, a drug commonly used for the treatment of multiple sclerosis, can also be used to target pancreatic cancer cells and make them more sensitive to chemotherapy.