The tuberculosis bacteria is notorious for its ability to stay dormant for years within the human body, evading the immune system and always one step away from causing aggressive infection. Now, a study from researchers at Translational Health Science and Technology Institute (THSTI), Faridabad, and Institute of Microbial Technology (IMTech), Chandigarh, has investigated a novel molecular pathway that helps the bacteria avoid the notice of the immune system.
Like a handful of other viruses, the novel coronavirus may also be capable of crossing the placental barrier in pregnant women and infecting the fetus. A recent study from researchers at ICMR-National Institute for Research in Reproductive Health (ICMR-NIRRH) and Indian Institute of Science (IISc), Bengaluru, has examined molecular players in the placenta which may be responsible for allowing the virus to access the developing fetus.
Tuberculosis is a common comorbidity in those infected with HIV/AIDS, and the two conditions are known to exacerbate one another. A new study from researchers at the Indian Institute of Science, Bengaluru demonstrates that Mycobacterium tuberculosis, the tuberculosis bacteria, can reactivate dormant HIV within the human body, a process that can potentially be targeted by specific drugs.
One of the main challenges in cancer chemotherapy is how to selectively kill tumour cells while leaving healthy cells alive. Researchers at the Indian Institute of Science Education and Research (IISER) Pune have come up with a novel approach where they use an artificially constructed ion channel and certain biochemical peculiarities of cancer cells to induce cell death in a highly targeted manner.
Early diagnosis is critical for the effective treatment of cancer and there has been a strong push for non-invasive and rapid techniques to detect malignant cells. In a new study, researchers from S N Bose National Centre for Basic Sciences, Saha Institute of Nuclear Physics, and Bose Institute, Kolkata have come up with a method to identify colon cancer cells using a biomarker that can be detected in low levels in bodily fluids.
Genetic variations and diversity both within and between populations play an important role in human health and disease. The Indo-US workshop on Human Diversity and Health Disparities brought together researchers from several different fields to discuss the importance of this often-neglected dimension in public health and biomedical research.
Maternal health is one of the major thrusts of India's healthcare strategy moving into the next decade, and new research has been shedding light onto important problems that need to be addressed in this sector. One of these is Gestational Diabetes Mellitus, a condition which can increase the risk of metabolic disorders for the newborn as well as the mother. A study by the Diabetes in Pregnancy Study group India recommends a simple screening procedure to help identify such patients and provide them with the necessary care.