Foetal bovine serum is a nutrient-rich additive widely used for in vitro cell culture studies. However, harvesting the serum involves inhuman methods, calling for replacing or reducing its use in experiments. Here is a report on one such ethical step by a team of researchers who found a novel technique to grow skin cells by drastically reducing bovine serum use.
Tuberculosis is a common comorbidity in those infected with HIV/AIDS, and the two conditions are known to exacerbate one another. A new study from researchers at the Indian Institute of Science, Bengaluru demonstrates that Mycobacterium tuberculosis, the tuberculosis bacteria, can reactivate dormant HIV within the human body, a process that can potentially be targeted by specific drugs.
Macrophages are an important category of immune cells that patrol our body to find and destroy pathogens, often by swallowing them whole - a process known as phagocytosis. A recent study by researchers at the Indian Association for the Cultivation of Science (IACS), Kolkata, has discovered how the physical properties of macrophages change in response to phagocytosis and how this, in turn, affects their function.
Just like animals, plants often face threats from their environment, including attacks by parasites, pests, and grazing animals. Unlike animals, however, plants cannot simply move away from the source of such threats. A new study from researchers at NIPGR, New Delhi, offers insights into the intricacies of the plant defence system and how it recognizes and responds to danger, particularly from insect pests.
A sustained collaborative effort from three very different laboratories, including a father-daughter scientific duo, has resulted in the observation that the neurotransmitter serotonin regulates energy levels in neurons with the help of Sirt1, a protein known for its role in ageing and lifespan regulation.
Since their initial discovery several decades ago, stem cells have faced intensive study due to their potential medical applications and fascinating biology. A question that has long interested scientists is how do stem cells continue to remain in an undifferentiated or 'uncommitted' state, unlike every other cell type in the body? Now, a new study from researchers at the National Centre for Cell Science (NCCS) sheds light on this unique problem.
The cell is a factory where every component needs to be in its proper place at the proper time for continued function and survival. A new study by researchers at the Indian Institute of Science, Bengaluru, explores how cells manage this remarkable feat of ensuring that the right molecules find their way to the right locations within the cell.