Globally Clinical Research has been in the forefront, for understanding the nature of the virus and trying diagnostics, therapeutics or preventive measures including vaccines, seeking insights on how to be prepared to face next infectious disease pandemic. In addition to clinical trials, epidemiological and socio-behavioral studies play a critical role in reducing morbidity and mortality and improving preparedness for future pandemics. 

Clinical Research of new therapies and vaccines raise special challenges in such Public Health Emergencies. Researchers, sponsors and funders have general obligations to make sure that studies are scientifically valid, have social value, involve equitable distribution of risks and benefits, and involve fair selection of participants There may, however, be a conflict between requiring valid scientific design and providing access to possibly beneficial interventions. Resolving this conflict involves attention to the choice of an appropriate control group, providing access to interventions to those who cannot participate in trials, and fast-tracking approvals for emergency use. 

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